Nearly immediately, PA officials blamed Hamas for what it called a cowardly assassination attempt against its prime minister, Rami Hamdallah, who had traveled to Gaza to take part in an inauguration ceremony of a wastewater treatment plant.
"The situation in Gaza must be solved for humanitarian reasons and for ensuring the security of Egypt and Israel", the White House said in a statement Wednesday.
No group has claimed responsibility for the bombing, which Hamdallah describes as an "assassination attempt".
Hamas shot back, saying such rapid accusations were unhelpful before in turn pointing the finger of blame at Israel.
For his part, Palestinian ambassador to Cairo Diab Allouh denied that Hamas was ever charged with the incident, in a response to allegations made by some media outlets.
Hamdallah said the attack would not end his government's commitment to continue with reconciliation and again called on Hamas to hand over all power in Gaza.More news: Jaguars reach 3-year deal with DJ Hayden
"We are talking about internal security - the police and the civil defence", he said.
Dahlan condemned the attack, noting that it aimed to damage the ongoing efforts to reach national reconciliation.
He said potential suspects are those that have an interest in maintaining the split.
Also on Tuesday, Abbas' spokesperson Nabil Abu Rudeineh blamed the attack on Hamas, decrying it as an "attack on the unity of the Palestinian people". Two of its three entry points are blockaded by Israel due to national security concerns.
The White House on Tuesday hosted 19 nations, including Israel and Arab Gulf states, to address the humanitarian crisis in Gaza, but the Palestinian Authority boycotted the meeting, angered by the Trump administration's policies on Jerusalem.
Hamdallah travelled to Rome Wednesday for a meeting of worldwide donors aimed at raising funds for the United Nations' agency for Palestinian refugees, which is facing desperate shortages after the U.S. froze tens of millions of dollars in aid. Palestinians are angered at Mr. Trump's decision late previous year to recognize Jerusalem as the capital of Israel, and to move the US embassy there from Tel Aviv.