Prof Hawking arrived at the University of Cambridge in 1962 as a PhD student and rose through the ranks to become the Lucasian Professor of Mathematics - a position once held by Sir Isaac Newton - in 1979.
His 1988 book "A Brief History of Time" became an global bestseller and brought him widespread fame.
"Alongside the benefits, A.I. will also bring dangers, like powerful autonomous weapons, or new ways for the few to oppress the many", he said in 2014 at the launch for the Centre for the Future of Intelligence at Cambridge University.
The disease spurred him to work harder but also contributed to the collapse of his two marriages, he wrote in a 2013 memoir My Brief History.
"I think his comment was that "not all of it happened but it was completely true". was his verdict on the film. We have this one life to appreciate the grand design of the universe and for that, I am extremely grateful". His theories unlocked a universe of possibilities that we & the world are exploring.
"I am an optimist and I believe that we can create AI for the good of the world".
Hawking's popular recognition became such that he appeared as himself on the television show "Star Trek: Next Generation" and his cartoon caricature appeared on "The Simpsons". He narrated a segment of the opening ceremony of the London Paralympic Games in August 2012, the year he turned 70.
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"We have lost a truly attractive mind, an astonishing scientist and the funniest man I have ever had the pleasure to meet", Redmayne said.
His most famous book explained the origins of the universe in terms a non scientist could relate to.
"To meet him and talk to him as a person, it was a wonderful opportunity", Sinclair says, as he looks through photos of the visit. Still, the book's discussion of concepts like time, space, black holes, and the Big Bang proved to be a bit complex for non-scientists, and Hawking liked to joke that it was the least-read, most-purchased book in history.
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In his doctoral thesis, which made waves in 1972, Bekenstein theorized that black holes had entropy, or disorder in their system, and subsequently, according to the laws of physics, a temperature. "But not me, never".
Apparently linking Hawking's decades-long battle with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease) with his own foot injury - which he should be fully recovered from in, like, May - Neymar posted a tweet showing him in a walking boot and wheelchair along with a quote from Hawking. I'm not afraid of death, but I'm in no hurry to die.
Hawking later married one of those nurses, Elaine Mason, whose former husband had designed Hawking's speech synthesiser, although the relationship did not last either. The pair divorced in 2007.
NASA tweeted: "Remembering Stephen Hawking, a renowned physicist and ambassador of science". After studying physics at Oxford University, he was in his first year of research work at Cambridge when he was diagnosed with motor neurone disease. Still, my disability is a part of me and Stephen's was a part of him.
Many tributes have flowed in following the death of legendary British physicist Stephen Hawking, but not all have quite gone to plan.
"I haven't had to lecture or teach undergraduates and I haven't had to sit on tedious and time-consuming committees". "I've been to talks Hawking has given and can not follow them myself".