Trump said the strikes were in coordination with France and the United Kingdom, adding that the goal of the campaign is to "establish a strong deterrent against the production, spread and use of chemical weapons".
The airstrikes included 105 weapons that were deployed against three targets in western Syria in a multinational effort that involved France and the United Kingdom and were in response to a suspected chemical attack last weekend that killed dozens near the capital of Damascus.
Keen to act decisively in the way his predecessor had failed, Donald Trump ordered missile strikes on an airbase that were little more than a rap on the knuckles for the Syrian government.
Moving to return to diplomacy, France said it was working with the United States and Britain on a draft resolution that would address chemical weapons use, the humanitarian crisis and the future of the peace process in Syria. Could not have had a better result. "Mission Accomplished!" Trump tweeted.
Dana W. White, the chief Pentagon spokeswoman, said that to her knowledge no one in the Defense Department communicated with Moscow in advance, other than the acknowledged use of a military-to-military hotline that has routinely helped minimize the risk of U.S.
"The time for talk ended last night", Haley told the UN Security Council. They were very effective.
After the announcement, the USA said strikes had been launched at 9pm EST (2am BST) and had destroyed important infrastructure at three sites connected with the Syrian regime's chemical weapons programme.
Trump's declaration of "mission accomplished" had an awkward historic ring.
"I spoke to the president this morning and he said, 'If the Syrian regime uses this poisonous gas again, the United States is locked and loaded, ' " Haley said.
"When our President draws a red line, our President enforces the red line", she said.
"British Prime Minister Theresa May said in London that the West had tried "every possible" diplomatic means to stop Assad from using chemical weapons". One of those tweets read.
Jaish al-Islam, the group that held Douma, said it only abandoned the town because of the chemical attack. The document points to a large number of "reliable" photos and videos of victims suffering from the symptoms of a chemical attack.
The U.S. argues that the horrific chemical weapons attack in the suburbs of Damascus last Saturday is a burden Russian Federation must bear, as it failed to ensure that the Syrian regime abandoned its chemical weapons, as the Obama-era agreement required.
The assessment also suggests that the Syrian government not only used chlorine in the attack on Douma, but that reported symptoms were also consistent with exposure to sarin, a deadly nerve agent.More news: Robert De Niro's Robert Mueller Grills Ben Stiller's Michael Cohen
The UN Security Council did not adopt a resolution from Russian Federation on Saturday that would have condemned the U.S. and its allies for a joint military strike on Syrian chemical weapons facilities. And Syria has a reason to flout worldwide law in this way; last weekend's barbaric attack achieved its desired effect, forcing recalcitrant rebels to give up an important piece of territory. Putin added that Russian military experts who inspected Douma found no trace of the attack.
Syrians are adamant that this was not a place to develop chemical weapons but rather a place of learning - a research institution where they developed things like pharmaceuticals.
A photo released on April 14, 2018 the twitter page of the Syrian governments central military media on April 14, 2018 shows an explosion on the outskirts of Damascus.
Speaking from rebel-held northern Syria, Abdulrazek told The Associated Press there were an estimated 50 warehouses around Syria that stored chemical weapons before the program was dismantled in 2013.
"[They must] engage seriously in negotiations to bring the seven year civil war to an end", he said.
"These three targets seemed to hit the sweet spot and do that", McKenzie said. "This is going to set the Syrian chemical weapon program back for years".
Mattis says the United States, along with France and the United Kingdom, struck because Syrian President Bashar Assad "did not get the message" when the USA launched airstrikes after a chemical attack in 2017.
"The only significance of this attack is that a stronger military alliance has been built between Britain, France and the United States".
The Syrian Observatory for Human Rights, a Britain-based monitor, said all the targets were linked to the Syrian Scientific Studies and Research Center (SSRC), which the United States has accused of weaponizing sarin.
Neither Syria nor its Russian or Iranian allies retaliated, Pentagon officials said.
The operation also drew support from the North Atlantic Treaty Organisation, the European Union, and other key U.S. allies.
Pentagon officials said the action "took out the heart" of Assad's chemical weapons arsenal.
The Russian military said that 103 cruise missiles were fired including Tomahawk missiles, but that Syrian air defense systems managed to intercept 71 cruise missiles.
The White House says the leaders agreed the airstrikes in Syria "were successful and necessary to deter" the future use of chemical weapons.