A victory may cement Uruguay's position as the group's leader, lining it most probably for a tough second-round clash against Spain or Portugal.
On Monday, a plane carrying Saudi Arabia's national football team caught fire en-route to the southern Russian city of Rostov-on-Don, just ahead of a World Cup match against Uruguay on June 20, according to the Guardian.
Unverified video footage showed the wing of the aeroplane in fire.
A Saudi Arabia statement said: "All the Saudi national team players have arrived safely and now are staying in their residence".More news: Federer Wins Mercedes Cup , Reclaims No. 1 Spot
The Saudi Football Association issued a statement saying that "The Saudi Football Federation wishes to reassure everyone about the safety of all the members of the mission of the national team after a minor technical malfunction in an engine".
After losing their first Group A game 5-0 against hosts Russia, Saudi Arabia take on Uruguay on Wednesday in their second World Cup fixture.
Muslera will also tie Ladislao Mazurkiewicz as the player to have made the most appearances for Uruguay at a World Cup.
Bizarrely, two-time World Cup champion Uruguay has never beaten the Green Falcons; Saudi Arabia won a friendly in 2002 while a 2014 friendly ended in a draw. And unusually, Barcelona striker Luis Suarez missed three golden chances to score.