At a meeting with her Conservative Party lawmakers on Monday, she was cheered and applauded by many as she warned them that internal squabbling could pave the way for socialist opposition leader Jeremy Corbyn to take power instead. His departure adds to a crisis over Brexit that threatens to tear apart Prime Minister Theresa May's government.
Talking to Julia Hartley-Brewer on talkRADIO's No Nonsense Breakfast he said: "Over the weekend, I only raised questions on what had been agreed because I was surprised that members of the cabinet had gone along with something that seemed on the face of it was tying us to the European Union one way or another".
The crisis swirling around the United Kingdom government and Brexit talks right now has been touted by some factions as a result of prime minister Theresa May's weak leadership. Hunt's post of health secretary has been taken over by culture, media and sport secretary Matt Hancock, as May struggled to keep control of dissenting voices within her top team.
10 Downing Street confirmed Hunt's appointment on Twitter, after he was seen visiting the Prime Minister's official residence earlier in the evening.
He said many MPs saw Mr Johnson's resignation as a "selfish act".
She then returned to Downing Street to fill the gaps left on the government benches by several resignations, sparked by the Brexit secretary, David Davis, who stepped down late on Sunday night.More news: British woman dies after Novichok nerve agent poisoning
During that campaign he travelled around the country in a Vote Leave bus controversially emblazoned with the claim that exiting the European Union would bring £350 million a week back to Britain to spend on the NHS.
Arch-Brexiteer Jacob Rees-Mogg said he did not believe there would be a vote of confidence in Mrs May by Tory MPs, but called on her to change her Brexit stance as he attacked the Cabinet deal on European Union withdrawal hammered out at a summit at Chequers last week.
"That dream is dying, suffocated by needless self-doubt".
The PM told MPs she wanted to recognise the work of the former Brexit secretary on steering through some of the "most important legislation for generations" and the "passion" that the outgoing foreign secretary had shown in promoting a "global Britain to the world".
Under Conservative Party rules, a confidence vote in a leader can be triggered if 48 lawmakers from May's Conservative Party request one.
"Nine ministers have now resigned from the two key Brexit departments since Article 50 was triggered". The UK government is in turmoil, but that has been the case for more than two years.